Pipecuronium (bromide)

CAT: 0804-HY-B0743A-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0743A-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Pipecuronium bromide is a potent long-acting nondepolarizing steroidal neuromuscular blocking agent (NMBA), and a bisquaternary ammonium compound. Pipecuronium bromide is a powerful competitive nAChR antagonist with a Kd of 3.06 μM[1][2][3][4][5].
CAS Number
[52212-02-9]
UNSPSC
12352005
Hazard Statement
H300, H312, H331
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pipecuronium-bromide.html
Purity
99.88
Solubility
DMSO : 150 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
C[C@@]1([C@H]2OC(C)=O)[C@](C[C@@H]2N3CC[N+](C)(C)CC3)([H])[C@@](CC[C@]4([H])[C@@]5(C[C@H](N6CC[N+](C)(C)CC6)[C@@H](OC(C)=O)C4)C)([H])[C@]5([H])CC1.[Br-].[Br-]
Molecular Formula
C35H62Br2N4O4
Molecular Weight
762.70
Precautions
H300, H312, H331
References & Citations
[1]Tassonyi E, et al. Reversal of Pipecuronium-Induced Moderate Neuromuscular Block with Sugammadex in the Presence of a Sevoflurane Anesthetic: A Randomized Trial. Anesth Analg. 2015 Aug;121 (2) :373-80.|[2]Tassonyi E, et al. Reversal of Deep Pipecuronium-Induced Neuromuscular Block With Moderate Versus Standard Dose of Sugammadex: A Randomized, Double-Blind, Noninferiority Trial. Anesth Analg. 2018 Dec;127 (6) :1344-1350.|[3]Alánt O, et al. First clinical experience with a new neuromuscular blocker pipecurium bromide. Arzneimittelforschung. 1980;30 (2a) :374-9.|[4]Töröcsik A, et al. Characterization of somatodendritic neuronal nicotinic receptors located on the myenteric plexus. Eur J Pharmacol. 1991 Sep 24;202 (3) :297-302.|[5]Kárpáti E, et al. Investigation of neuromuscular blocking agents at Richter Ltd. Acta Pharm Hung. 2002;72 (1) :37-48.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched

Related Products

CatalogName
HY-106564AFlutropium (bromide)
HY-105771Parapenzolate (bromide)
HY-W127652-01Didecyldimethylammonium (bromide)
HY-108030Bencycloquidium bromide
HY-W127648Heptadecyltrimethylammonium (bromide)
HY-W099576-01Ethylhexadecyldimethylammonium (bromide)
HY-W699398Eicosyltriethylammonium bromide
HY-D0172-01Tetrabutylammonium (bromide)
HY-172342MitoA (bromide)
HY-W099642-01Trimethyloctylammonium (bromide)

Alternative Products

CatalogName
TRC-P479780-50MGPipecuronium Bromide
TRC-D842390-50MGDesacetyl Pipecuronium Bromide
RM-P093303-01Pipecuronium bromide Impurity 3
RM-P093302-01Pipecuronium bromide Impurity 2
TRC-D842380-25MGDi-desacetyl Pipecuronium Bromide
29309654-100gHexadecyltrimethylammonium bromide (Cetyltrimethylammonium bromide)
CB0105Cetyldimethylethyl ammonium bromide (Ethylhexadecyldimethylammonium bromide)
O5553-02Octylonium Bromide (Spasmonen. Otilonium Bromide)
RM-T201631-01Tiotropium Bromide EP Impurity H Bromide
I8499Ipratropium Bromide Monohydrate (Atropine Isopropyl Bromide)

Popular Products