Products for Research Use Only
RegisterLogin

Pipecolic acid

CAT: 0804-HY-Y0669-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-Y0669-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Pipecolic acid is a metabolite of lysine and an important precursor for many useful microbial secondary metabolites. Pipecolic acid slows ferroptosis in diabetic retinopathy by inhibiting the YAP-GPX4 signaling pathway. In addition, Pipecolic acid can be used as a diagnostic marker for pyridoxine-dependent epilepsy[1][2][3].
CAS Number
535-75-1
UNSPSC
12352200
Hazard Statement
H315, H319, H335
Target
Endogenous Metabolite; Ferroptosis; Glutathione Peroxidase; YAP
Type
Biochemical Assay Reagents
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Pipecolic_acid.html
Purity
99.92
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
O=C(O)C1CCCCN1
Molecular Formula
C6H11NO2
Molecular Weight
129.16
Precautions
H315, H319, H335
References & Citations
[1]He M, et al. Pipecolic acid in microbes: biosynthetic routes and enzymes. J Ind Microbiol Biotechnol. 2006 Jun;33 (6) :401-7.|[2]Plecko B, et, al. Pipecolic acid as a diagnostic marker of pyridoxine-dependent epilepsy. Neuropediatrics. 2005 Jun;36 (3) :200-5.|[3]Liying Luo, et al. "Pipecolic acid mitigates ferroptosis in diabetic retinopathy by regulating GPX4-YAP signaling." Biomedicine & Pharmacotherapy 169 (2023) : 115895.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Isoform
GPX4; Human Endogenous Metabolite; Microbial Metabolite

Related Products

CatalogName
HY-Y0181-01D-Pipecolinic acid
HY-Y0181R-01D-Pipecolinic acid (Standard)
HY-W048995-01D-6-Oxo-pipecolinic acid
HY-140589Acid-PEG4-S-PEG4-acid
HY-140112-01Acid-PEG2-SS-PEG2-acid
HY-140113-01Acid-PEG3-SS-PEG3-acid
HY-W096114-01Acid-PEG8-S-S-PEG8-acid
HY-140114-01Acid-PEG4-S-S-PEG4-acid
HY-N8563Masticadienonic acid
HY-N8543Gliocladic acid

Alternative Products

CatalogName
286589-01Pipecolic acid
019747D-Pipecolic Acid
TRC-P479750-100MGL-Pipecolic Acid
TRC-P479760-1GDL-Pipecolic Acid
sc-286951Z-pipecolic acid

Popular Products