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SHS4121705

CAT: 0804-HY-137922-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-137922-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SHS4121705 is an orally effective mitochondrial uncoupling agent with an IC50 of 4.3 μM in L6 myoblasts. SHS4121705 can be used in the study of non-alcoholic steatohepatitis (NASH) [1].
CAS Number
2379550-82-8
UNSPSC
12352005
Target
Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/shs4121705.html
Smiles
O=C1N=C2C(N=C1NC3=CC=C(OC(F)(F)F)C=C3)=NON2
Molecular Formula
C11H6F3N5O3
Molecular Weight
313.19
References & Citations
[1]Salamoun JM, et al. 6-Amino[1,2,5]oxadiazolo[3,4-b]pyrazin-5-ol Derivatives as Efficacious Mitochondrial Uncouplers in STAM Mouse Model of Nonalcoholic Steatohepatitis. J Med Chem. 2020 Jun 11;63 (11) :6203-6224.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19191984-01SHS4121705

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