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SHS4121705

CAT: 0931-T35636-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T35636-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2379550-82-8
Target
Others, Mitochondrial Metabolism
Related Pathways
Others, Metabolism
Bioactivity
SHS4121705 is an orally bioavailable mitochondrial uncoupler.1It increases oxygen consumption rate in L6 rat myoblast cells with an EC50value of 4.3 μM. SHS4121705 (25 mg/kg per day in the diet) reduces hepatic steatosis, liver triglyceride levels, and plasma alanine aminotransferase (ALT) levels in Stelic animal model (STAM) mice, a model of non-alcoholic steatohepatitis (NASH) .
Smiles
N(C1=NC=2C(=NC1=O)NON2)C3=CC=C(OC(F)(F)F)C=C3
Molecular Formula
C11H6F3N5O3
Molecular Weight
313.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19191984-01SHS4121705

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