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Lanoconazole (Standard)

CAT: 0804-HY-14282R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14282R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lanoconazole (Standard) is the analytical standard of Lanoconazole. This product is intended for research and analytical applications. Lanoconazole is a potent and orally active imidazole antifungal agent, shows a broad spectrum of activity against fungi in vitro and in vivo[1]. Lanoconazole interferes with ergosterol biosynthesis by inhibiting sterol 14-alpha demethylase and blocking fungal membrane ergosterol biosynthesis. Lanoconazole can be used for the investigation of dermatophytosis and onychomycosis[1][2].
CAS Number
101530-10-3
UNSPSC
12352005
Target
Fungal; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Others
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lanoconazole-standard.html
Smiles
N#C/C(N1C=CN=C1)=C2SC(C(C=CC=C3)=C3Cl)CS\2
Molecular Formula
C14H10ClN3S2
Molecular Weight
319.83
References & Citations
[1]Shokoohi GR, et al. In Vitro Activities of Luliconazole, Lanoconazole, and Efinaconazole Compared with Those of Five Antifungal Drugs against Melanized Fungi and Relatives.Antimicrob Agents Chemother. 2017 Oct 24;61 (11) . pii: e00635-17.|[2]Nakamura A, et al. Anti-inflammatory effect of lanoconazole on 12-O-tetradecanoylphorbol-13-acetate- and 2,4,6-trinitrophenyl chloride-induced skin inflammation in mice.Mycoses. 2020 Feb;63 (2) :189-196.|[3]Furukawa K, et al. Lanoconazole, a new imidazole antimycotic compound, protects MAIDS mice against encephalitis caused by Cryptococcus neoformans.J Antimicrob Chemother. 2000 Sep;46 (3) :443-50.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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