Vimentin (Mesenchymal Cell Marker) Recombinant Rabbit Monoclonal Antibody [Clone VIM/6576R]

• CAS Number:

  9000-83-3

• Gene Name:

  [VIM]

• NCBI Gene ID:

  7431

• Reactivity:

  Cat, Chicken, Cow, Dog, Horse, Human, Pig

• Storage Conditions:

  Antibody without azide - store at -20° to -80°C. Non-hazardous. No MSDS required.

• Specificity:

  This MAb reacts with a 58kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP s) such as desmin, keratin, neurofilament, and glial fibrillary acid protein.Anti-vimentin alone is of limited value as a test tool; however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.

• Other Gene Names:

  [VIM; VIM]

• Short Name:

  [Vimentin]

• Other Product Names:

  [vimentin; Vimentin; vimentin; vimentin]

• NCBI GI Number:

  62414289

• NCBI Accession Number:

  NP_003371.2

• NCBI GB Accession Number:

  NM_003380.3

• Uniprot Accession Number:

  P08670