Vimentin (Mesenchymal Cell Marker)

Vimentin (Mesenchymal Cell Marker)

• Gene Name: [VIM]
• NCBI Gene ID: 7431
• Reactivity: Human
  Does not react with Mouse or Rat.
• Storage Conditions: Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: This MAb reacts with a 58kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP s) such as desmin, keratin, neurofilament, and glial fibrillary acid protein.Anti-vimentin alone is of limited value as a tool; however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.
• Other Gene Names: [VIM; VIM]
• Short Name: [Vimentin]
• Other Product Names: [vimentin; Vimentin; vimentin; vimentin]
• NCBI GI Number: 62414289
• NCBI Accession Number: NP_003371.2
• NCBI GB Accession Number: NP_003371.2
• Uniprot Accession Number: P08670