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CD137L/4-1BBL/TNFSF9

CAT: 0544-MBS4381708-01Size: 0.5 mLDry Ice: NoHazardous: No
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CAT#:0544-MBS4381708-01Size:0.5 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[TNFSF9]
NCBI Gene ID
8744
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
TNFSF9 / 4-1BBL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9 / 4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9 / 4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. It has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine is required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.
Other Gene Names
[TNFSF9; TNFSF9; CD137L; TNLG5A; 4-1BB-L; 4-1BBL]
Short Name
[CD137L/4-1BBL/TNFSF9]
Other Product Names
[tumor necrosis factor ligand superfamily member 9; Tumor necrosis factor ligand superfamily member 9; tumor necrosis factor ligand superfamily member 9; TNF superfamily member 9; 4-1BB ligand]
NCBI GI Number
4507609
NCBI Accession Number
NP_003802.1
NCBI GB Accession Number
NP_003802.1
Uniprot Accession Number
P41273

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