Coagulation Factor VII/F7

CAT: 0544-MBS4381660-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
CAT#:0544-MBS4381660-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[F7]
NCBI Gene ID
2155
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Coagulation Factor VII (serum prothrombin conversion accelerator, proconvertin, F7, Factor VII) is a 406 amino acid, vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor. Factor IX A, Factor X A, Factor XII A or Thrombin-mediated proteolytic cleavage of Factor VII at Arg 152-Ile 153 generates Factor VII A, an active serine protease composed of a catalytic heavy chain disulfide linked to a light chain, containing two EGF-like domains. Mutations at the F7 locus that lead to Factor VII deficiencies are generally asymptomatic or phenotypically uncharacterized, with hemorrhagic diathesis occurring at extremely low levels.
Other Gene Names
[F7; F7; SPCA; SPCA]
Short Name
[VII/F7]
Other Product Names
[coagulation factor VII isoform a preproprotein; Coagulation factor VII; coagulation factor VII; coagulation factor VII; Proconvertin; Serum prothrombin conversion accelerator]
NCBI GI Number
4503645
NCBI Accession Number
NP_000122.1
NCBI GB Accession Number
NP_000122.1
Uniprot Accession Number
P08709

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