Creatine Kinase MM

• Gene Name:

  [CKM]

• NCBI Gene ID:

  1158

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

• Other Gene Names:

  [CKM; CKM; CKMM; M-CK; CPK-M; CKMM]

• Short Name:

  [Creatine Kinase MM]

• Other Product Names:

  [creatine kinase M-type; Creatine kinase M-type; creatine kinase M-type; creatine kinase, M-type; Creatine kinase M chain; M-CK]

• NCBI GI Number:

  21536288

• NCBI Accession Number:

  NP_001815.2

• NCBI GB Accession Number:

  NP_001815.2

• Uniprot Accession Number:

  P06732