Apolipoprotein A1/APOA1

Apolipoprotein A1/APOA1

• Gene Name: [APOA1]
• NCBI Gene ID: 335
• Reactivity: Human
• Storage Conditions: Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: Apolipoproteins are protein components of plasma lipoproteins. The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids (FFA). The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles. ApoA-IV is a potent activator of LCAT in vitro. The human apoA-V gene encodes a 366 amino acid protein that is believed to be an important determinant of plasma triglyceride levels.
• Other Gene Names: [APOA1; APOA1; HPALP2; apo(a); Apo-AI; ApoA-I]
• Short Name: [Apolipoprotein A1/APOA1]
• Other Product Names: [APOA1, partial; Apolipoprotein A-I; apolipoprotein A-I; apolipoprotein A1; Apolipoprotein A1Cleaved into the following chain:Truncated apolipoprotein A-I; Alternative name(s):; Apolipoprotein A-I(1-242)]
• NCBI GI Number: 553183
• NCBI Accession Number: AAA51746.1
• Uniprot Accession Number: P02647