Apolipoprotein A1/APOA1

• Gene Name:

  [APOA1]

• NCBI Gene ID:

  335

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Apolipoproteins are protein components of plasma lipoproteins. The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids (FFA). The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles. ApoA-IV is a potent activator of LCAT in vitro. The human apoA-V gene encodes a 366 amino acid protein that is believed to be an important determinant of plasma triglyceride levels.

• Other Gene Names:

  [APOA1; APOA1; HPALP2; apo(a); Apo-AI; ApoA-I]

• Short Name:

  [Apolipoprotein A1/APOA1]

• Other Product Names:

  [APOA1, partial; Apolipoprotein A-I; apolipoprotein A-I; apolipoprotein A1; Apolipoprotein A1Cleaved into the following chain:Truncated apolipoprotein A-I; Alternative name(s):; Apolipoprotein A-I(1-242)]

• NCBI GI Number:

  553183

• NCBI Accession Number:

  AAA51746.1

• Uniprot Accession Number:

  P02647