Ki-67 (Proliferating Cell Marker)

• Gene Name:

  [MKI67]

• NCBI Gene ID:

  4288

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.

• Other Gene Names:

  [MKI67; MKI67; KIA; MIB-; MIB-1; PPP1R105]

• Short Name:

  [Ki-67]

• Other Product Names:

  [proliferation marker protein Ki-67 isoform 2; Antigen KI-67; proliferation marker protein Ki-67; marker of proliferation Ki-67]

• NCBI GI Number:

  225543215

• NCBI Accession Number:

  NP_001139438.1

• NCBI GB Accession Number:

  NP_001139438.1

• Uniprot Accession Number:

  P46013