E-Cadherin/CD324 (Intercellular Junction Marker)

CAT: 0544-MBS4381453-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
CAT#:0544-MBS4381453-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Gene Name
[CDH1]
NCBI Gene ID
999
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Recognizes a protein of 120-80kDa, identified as E-cadherin. Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as -catenin, to regulate cadherin function. E-cadherin plays an important role in epithelial cell adhesion. A decreased expression of E-cadherin is associated with metastatic potential and poor prognosis in breast cancer, prostate and esophageal cancer. In combination with p120 Catenin, it is useful for the differentiation between ductal (E-cadherin +) and lobular (E-cadherin -) breast carcinomas. It may also help of mesothelioma.
Other Gene Names
[CDH1; CDH1; UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324; CDHE; UVO; E-cadherin]
Short Name
[E-Cadherin/CD324]
Other Product Names
[cadherin-1 isoform 1 preproprotein; Cadherin-1; cadherin-1; cadherin 1; CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin]
NCBI GI Number
4757960
NCBI Accession Number
NP_004351.1
NCBI GB Accession Number
NP_004351.1
Uniprot Accession Number
P12830

Popular Products