CD137L/4-1BBL/TNFSF9

• Gene Name:

  [TNFSF9]

• NCBI Gene ID:

  8744

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  TNFSF9/4-1BBL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. It has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine is required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.

• Other Gene Names:

  [TNFSF9; TNFSF9; CD137L; TNLG5A; 4-1BB-L; 4-1BBL]

• Short Name:

  [CD137L/4-1BBL/TNFSF9]

• Other Product Names:

  [tumor necrosis factor ligand superfamily member 9; Tumor necrosis factor ligand superfamily member 9; tumor necrosis factor ligand superfamily member 9; TNF superfamily member 9; 4-1BB ligand]

• NCBI GI Number:

  4507609

• NCBI Accession Number:

  NP_003802.1

• NCBI GB Accession Number:

  NP_003802.1

• Uniprot Accession Number:

  P41273