CD71/Transferrin Receptor (TFRC)

• Gene Name:

  [TFRC]

• NCBI Gene ID:

  7037

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 4 to 8 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

• Other Gene Names:

  [TFRC; TFRC; T9; TR; TFR; p90; CD71; TFR1; TRFR; IMD46; TR; TfR; TfR1; Trfr; sTfR]

• Short Name:

  [CD71/Transferrin Receptor (TFRC)]

• Other Product Names:

  [transferrin receptor protein 1 isoform 1; Transferrin receptor protein 1; transferrin receptor protein 1; transferrin receptor; T9; p90]

• NCBI GI Number:

  189458819

• NCBI Accession Number:

  NP_001121620.1

• NCBI GB Accession Number:

  NP_001121620.1

• Uniprot Accession Number:

  P02786