HLA-DRB (MHC II)

HLA-DRB (MHC II)

• Gene Name: [HLA-DRB]
• NCBI Gene ID: 3123
• Reactivity: Human, Baboon, Chimpanzee, Monkey, Squirrel, Dog
• Storage Conditions: Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: This MAb reacts with the HLA-DRB3 antigen, a member of MHC class II molecules.It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
• Other Gene Names: [HLA-DRB1; HLA-DRB1; SS1; DRB1; HLA-DRB; HLA-DR1B; HLA-DRB2]
• Short Name: [HLA-DRB]
• Other Product Names: [major histocompatibility complex, class II, DR beta 1; HLA class II histocompatibility antigen, DRB1-15 beta chain; major histocompatibility complex, class II, DR beta 1; major histocompatibility complex, class II, DR beta 1; DW2.2/DR2.2; MHC class II antigen DRB1*15]
• NCBI GI Number: 155030211
• NCBI Accession Number: NP_002115.2
• NCBI GB Accession Number: NP_002115.2
• Uniprot Accession Number: P01911