GP2 (Glycoprotein 2)/ZAP75

CAT: 0544-MBS4380951-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
CAT#:0544-MBS4380951-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[GP2]
NCBI Gene ID
2813
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
Other Gene Names
[GP2; GP2; ZAP75]
Short Name
[GP2 (Glycoprotein 2)/ZAP75]
Other Product Names
[glycoprotein 2 (zymogen granule membrane), isoform CRA_d; Pancreatic secretory granule membrane major glycoprotein GP2; pancreatic secretory granule membrane major glycoprotein GP2; glycoprotein 2; Pancreatic zymogen granule membrane protein GP-2; ZAP75]
NCBI GI Number
119570698
NCBI Accession Number
EAW50313.1
Uniprot Accession Number
P55259

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