Drebrin 1 (DBN1)

Drebrin 1 (DBN1)

• Gene Name: [DBN1]
• NCBI Gene ID: 1627
• Reactivity: Human
• Storage Conditions: Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2); and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.
• Other Gene Names: [DBN1; DBN1; D0S117E; D0S117E]
• Short Name: [Drebrin 1 (DBN1)]
• Other Product Names: [drebrin isoform a; Drebrin; drebrin; drebrin 1; Developmentally-regulated brain protein]
• NCBI GI Number: 18426915
• NCBI Accession Number: NP_004386.2
• NCBI GB Accession Number: NP_004386.2
• Uniprot Accession Number: Q16643