Drebrin 1 (DBN1)

• Gene Name:

  [DBN1]

• NCBI Gene ID:

  1627

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2); and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.

• Other Gene Names:

  [DBN1; DBN1; D0S117E; D0S117E]

• Short Name:

  [Drebrin 1 (DBN1)]

• Other Product Names:

  [drebrin isoform a; Drebrin; drebrin; drebrin 1; Developmentally-regulated brain protein]

• NCBI GI Number:

  18426915

• NCBI Accession Number:

  NP_004386.2

• NCBI GB Accession Number:

  NP_004386.2

• Uniprot Accession Number:

  Q16643