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BTLA

CAT: 0544-MBS4380827-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
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CAT#:0544-MBS4380827-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[BTLA]
NCBI Gene ID
151888
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
B and T lymphocyte attenuator (BTLA) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T-cell activation. BTLA is similar to CTLA-4 and PD-1, all of which are coinhibitory receptors belonging to the CD28 family. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family counter receptors. Rather, the herpesvirus entry mediator (HVEM), a TNF receptor, acts as a molecular switch that modulates T-cell activation by propagating inhibitory signals through BTLA. The BTLAHVEM interaction is conserved between Mouse and human, suggesting that this system is an important pathway regulating lymphocyte activation.
Other Gene Names
[BTLA; BTLA1; CD272]
Short Name
[BTLA]
Other Product Names
[BTLA protein, partial; B- and T-lymphocyte attenuator; B and T lymphocyte associated]
NCBI GI Number
78070623

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