CD68 (Macrophage Marker)

• Gene Name:

  [CD68]

• NCBI Gene ID:

  968

• Reactivity:

  Human. Others not known.

• Storage Conditions:

  Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  This antibody recognizes a glycoprotein of 110kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.

• Other Gene Names:

  [CD68; CD68; GP110; LAMP4; SCARD1]

• Short Name:

  [CD68]

• Other Product Names:

  [macrosialin isoform B; Macrosialin; macrosialin; CD68 molecule; Gp110; CD_antigen: CD68]

• NCBI GI Number:

  91199550

• NCBI Accession Number:

  NP_001035148.1

• NCBI GB Accession Number:

  NM_001040059.1

• Uniprot Accession Number:

  P34810