14-3-3E/Tryptophan 5-Monooxygenase

14-3-3E/Tryptophan 5-Monooxygenase

• Gene Name: [YWHAE]
• NCBI Gene ID: 124323
• Reactivity: Human. Others not tested.
• Storage Conditions: Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia.
• Other Gene Names: [Rps23; Rps23]
• Short Name: [14-3-3E/Tryptophan 5-Monooxygenase]
• Other Product Names: [40S ribosomal protein S23; 40S ribosomal protein S23; 40S ribosomal protein S23; ribosomal protein S23]
• NCBI GI Number: 17530965
• NCBI Accession Number: NP_511172.1
• NCBI GB Accession Number: NM_078617.3
• Uniprot Accession Number: P62268