MUC1/CA15-3/EMA/CD227 (Epithelial Marker)

MUC1/CA15-3/EMA/CD227 (Epithelial Marker)

• Gene Name: [MUC1]
• NCBI Gene ID: 4582
• Reactivity: Human. Others not known.
• Storage Conditions: Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: In Western blotting, it recognizes proteins in MW range of 265-400kDa, identified as different glycoforms of EMA. This MAb reacts with the DTRP epitope in the tandem repeats. The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain, which is involved in cell signaling, through phosphorylations and protein-protein interactions. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinoma tissues. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
• Other Gene Names: [MUC1; MUC1; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; PUM; MUC-1; CA 15-3; KL-6; PUM; PEM; EMA; MUC1-NT; MUC1-alpha; MUC1-beta]
• Short Name: [MUC1/CA15-3/EMA/CD227]
• Other Product Names: [mucin-1 isoform 2; Mucin-1; mucin-1; mucin 1, cell surface associated; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3]
• NCBI GI Number: 67189007
• NCBI Accession Number: NP_001018016.1
• NCBI GB Accession Number: NM_001018016.2
• Uniprot Accession Number: P15941