ATG5 (Autophagy Marker)

• Gene Name:

  [ATG5]

• NCBI Gene ID:

  9474

• Reactivity:

  Human. Others not known.

• Specificity:

  The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. The ATG5 protein is essential for autophagy; a process that is usually beneficial for cells to self-degrade their own components when they are no longer useful.

• Other Gene Names:

  [ATG5; ATG5; ASP; APG5; APG5L; hAPG5; SCAR25; APG5-LIKE; APG5L; ASP]

• Short Name:

  [ATG5]

• Other Product Names:

  [autophagy protein 5 isoform a; Autophagy protein 5; autophagy protein 5; autophagy related 5; APG5-like; Apoptosis-specific protein]

• NCBI GI Number:

  554790362

• NCBI Accession Number:

  NP_001273035.1

• NCBI GB Accession Number:

  NM_001286106.1

• Uniprot Accession Number:

  Q9H1Y0