CD43 (T-Cell Marker)

CD43 (T-Cell Marker)

• Gene Name: [CD43]
• NCBI Gene ID: 6693
• Reactivity: Human. Others not known.
• Storage Conditions: Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43 [Workshop IV]. Epitope of MAb Bra7G is clearly different from that of MAb rSPN/839, called "b" as opposed to "a" for rSPN/839. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors of lymphoma.
• Other Gene Names: [SPN; SPN; LSN; CD43; GALGP; GPL115; CD43; CD43ct]
• Short Name: [CD43]
• Other Product Names: [leukosialin; Leukosialin; leukosialin; sialophorin; GPL115]
• NCBI GI Number: 71979937
• NCBI Accession Number: NP_001025459.1
• NCBI GB Accession Number: NM_001030288.3
• Uniprot Accession Number: P16150