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SUB1 antibody

CAT: 0710-FNab10363Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10363Size:100 µg
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Background
General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA) .
Synonyms
Activated RNA polymerase II transcriptional coactivator p15|Positive cofactor 4 (PC4) |SUB1 homolog|p14|SUB1|PC4|RPO2TC1
Gene ID
10923
UniProt
P53999
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SUB1 homolog
Target
SUB1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
17 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Immunogen Sequence
62-127aa

UniProtKB · P53999

Activated RNA polymerase II transcriptional coactivator p15

TCP4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P53999
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SUB1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q96L29
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-binding

Cellular component

Nucleus

Biological process

TranscriptionTranscription regulation

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