3'-Hydroxy Repaglinide

CAT: 0804-HY-135335-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-135335-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
3'-Hydroxy Repaglinide is a main CYP2C8 metabolite of Repaglinide. Repaglinide is a carbamoylmethyl benzoic acid (CMBA) derivative, which recently has become available for the treatment of type II diabetes[1][2].
CAS Number
[874908-14-2]
UNSPSC
12352005
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/3-hydroxy-repaglinide.html
Purity
98.20
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CC=C(CC(NC(C2=CC=CC=C2N3CC(O)CCC3)CC(C)C)=O)C=C1OCC
Molecular Formula
C27H36N2O5
Molecular Weight
468.59
References & Citations
[1]A liquid chromatography-tandem mass spectrometry analysis of nine cytochrome P450 probedrugs and their corresponding metabolites in human serum and urine. Anal Bioanal Chem. 2017 Jan;409 (1) :251-268.|[2]Honkalammi J, et al. Mechanism-based inactivation of CYP2C8 by gemfibrozil occurs rapidly in humans. Clin Pharmacol Ther. 2011 Apr;89 (4) :579-86.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-15209-01Repaglinide
HY-15209R-01Repaglinide (Standard)
HY-15209S-01Repaglinide-d5
HY-143809SRepaglinide M1-d5
HY-154749SRepaglinide M2-d5
HY-CE008623-Hydroxy-3- (3-hydroxy-4-methoxyphenyl) propionyl-CoA
HY-W818693-013-Hydroxy-3-phenylpentanamide
HY-129697-013-Hydroxy Medetomidine
HY-133111-013-Hydroxy agomelatine
HY-138151-013'-Hydroxy stanozolol

Alternative Products

CatalogName
MF-0006842-013'-Hydroxy Repaglinide
MF-00573633-Hydroxy Repaglinide-d5
TRC-H953280-10MG3’-Hydroxy Repaglinide (Mixture of Diastereomers)
sc-2097433'-Hydroxy Repaglinide (Mixture of Diastereomers)
TRC-H953282-1MG3’-Hydroxy Repaglinide-d5(Mixture of Diastereomers)
MBS6046623-013'-Hydroxy Repaglinide Ethyl Ester (Mixture of Diastereomers)
0144743’-Hydroxy Repaglinide Ethyl Ester (Mixture of Diastereomers)
RM-R160729-01Repaglinide Impurity 3
TRC-H946335-10MG3’-Hydroxy-3’-O-methoxymethyl Repaglinide Ethyl Ester(Mixture of Diastereomers)
MBS6080858-013'-Hydroxy-3'-O-methoxymethyl Repaglinide Ethyl Ester (Mixture of Diastereomers)

Popular Products