Compound C108

• Description :

  Compound C108 is a G3BP2 inhibitor. Compound C108 also targeted stress granule-associated proteins and Gtpase-activating protein (SH3 domain) binding protein 2. Compound C108 potently inhibits esophageal squamous cell carcinoma (ESCC) cell metastasis[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319

• Target :

  Others

• Type :

  Reference compound

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/compound-c108.html

• Concentration :

  10mM

• Purity :

  99.32

• Solubility :

  DMSO : 25 mg/mL (ultrasonic)

• Smiles :

  O=C(N/N=C(C1=CC=CC=C1O)\C)C2=CC=CC=C2O

• Molecular Formula :

  C15H14N2O3

• Molecular Weight :

  270.28

• Precautions :

  H315, H319

• References & Citations :

  [1]Gupta N, et al. Stress granule-associated protein G3BP2 regulates breast tumor initiation. Proc Natl Acad Sci U S A. 2017 Jan 31;114 (5) :1033-1038. |[2]Zheng Y, et al. G3BP2 regulated by the lncRNA LINC01554 facilitates esophageal squamous cell carcinoma metastasis through stabilizing HDGF transcript. Oncogene. 2022 Jan;41 (4) :515-526.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [15533-09-2]