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Compound C108

CAT: 0804-HY-131649-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-131649-01Size:5 mg
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Description
Compound C108 is a G3BP2 inhibitor. Compound C108 also targeted stress granule-associated proteins and Gtpase-activating protein (SH3 domain) binding protein 2. Compound C108 potently inhibits esophageal squamous cell carcinoma (ESCC) cell metastasis[1][2].
CAS Number
[15533-09-2]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/compound-c108.html
Concentration
10mM
Purity
99.32
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(N/N=C(C1=CC=CC=C1O)\C)C2=CC=CC=C2O
Molecular Formula
C15H14N2O3
Molecular Weight
270.28
Precautions
H315, H319
References & Citations
[1]Gupta N, et al. Stress granule-associated protein G3BP2 regulates breast tumor initiation. Proc Natl Acad Sci U S A. 2017 Jan 31;114 (5) :1033-1038. |[2]Zheng Y, et al. G3BP2 regulated by the lncRNA LINC01554 facilitates esophageal squamous cell carcinoma metastasis through stabilizing HDGF transcript. Oncogene. 2022 Jan;41 (4) :515-526.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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