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Medronic acid

CAT: 0804-HY-108309-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-108309-01Size:100 mg
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Description
Medronic acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has an affinity for the surface of hydroxyapatite crystals in the bone matrix and adheres to them. Medronic acid can be used in complex with radioisotopes in bone imaging. Due to its strong metal chelating ability, medronic acid is also used as a water treatment chemical. In addition, medronic acid is used as a solvent additive to improve peak shape and signal of metal-sensitive metabolites in LC/MS analysis[1][2].
CAS Number
1984-15-2
Product Name Alternative
Methylenediphosphonic acid
UNSPSC
12352211
Hazard Statement
H314
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Medronic_acid.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=P(O)(O)CP(O)(O)=O
Molecular Formula
CH6O6P2
Molecular Weight
176.00
Precautions
H314
References & Citations
[1]Ohta Y, et al. Salt Tolerance Enhancement of Liquid Chromatography-Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Using Matrix Additive MethylenediphosphonicAcid. Mass Spectrom (Tokyo) . 2014;3 (1) :A0031.|[2]Lin Y T, et al. Using an In-Sample Addition of Medronic Acid for the Analysis of Purine-and Pyrimidine-Related Derivatives and Its Application in the Study of Lung Adenocarcinoma A549 Cell Lines by LC–MS/MS[J]. Journal of Proteome Research, 2023, 22 (5) : 1434-1445.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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