ε-Poly-L-lysine (hydrochloride) (MV 2000-5000)

• UNSPSC Description:

  ε-Poly-L-lysine hydrochloride (MV 2000-5000) is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine hydrochloride inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine hydrochloride has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine hydrochloride can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine hydrochloride is also used as a liposome stabilizer[1][2][3][4].

• Target Antigen:

  Bacterial

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/ε-poly-l-lysine-hydrochloride-mv-2000-5000.html

• Solubility:

  H2O : 100 mg/mL (ultrasonic)

• Smiles:

  CNC([C@H](CCCCC)N)=O.[n].Cl

• Molecular Weight:

  2000-5000

• References & Citations:

  [1]Wang Z, et al. Metabolomic Analysis of Biosynthesis Mechanism of ε-Polylysine Produced by Streptomyces diastatochromogenes. Front Bioeng Biotechnol. 2021 Jul 30;9:698022.|[2]Alemán A, et al. A novel functional wrapping design by complexation of ε-polylysine with liposomes entrapping bioactive peptides[J]. Food and Bioprocess Technology, 2016, 9: 1113-1124.|[3]Yingying M, et al. pH-Sensitive ε-polylysine/polyaspartic acid/zein nanofiber membranes for the targeted release of polyphenols. Food Funct. 2022 Jun 20;13(12):6792-6801.|[4]Zhou X, et al. Elaboration and characterization of ε-polylysine‑sodium alginate nanoparticles for sustained antimicrobial activity. Int J Biol Macromol. 2023 Aug 16;251:126329.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported