GPR35 agonist 4

GPR35 agonist 4

• CAS Number: 871085-49-3
• UNSPSC Description: GPR35 agonist 4 (compound 10) is a potent GPR35 agonist with an pEC50 of 5.86. GPR35 agonist 4 shows high potency human and rat GPR35. Mutation of arginine 3.36 eliminates agonist function of GPR35 agonist 4[1].
• Target Antigen: GPR35
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/gpr35-agonist-4.html
• Purity: 99.0
• Solubility: DMSO : 27.9 mg/mL (ultrasonic)
• Smiles: O=C(NC(S/1)=O)C1=C\C2=CC=C(C=C2)OCC(O)=O
• Molecular Weight: 279.27
• References & Citations: [1]Jenkins L, et al. Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα₁₃ and β-arrestin-2. Br J Pharmacol. 2011 Feb;162(3):733-48.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported