α-Amylase-IN-3

α-Amylase-IN-3

• CAS Number: 93944-58-2
• UNSPSC Description: α-Amylase-IN-3 (Compound 4) is a none-competitive type of α-Amylase inhibitor with an IC50 value of 18.04 μM, which also has radical scavenging activities (DPPH and ABTS) with IC50 values of 16.04 μM (DPPH) and 16.99 μM (ABTS), respectively. α-Amylase-IN-3 has good protein–ligand interactions profile against α-Amylase. α-Amylase-IN-3 may have pharmacological activities such as anti-oxidative, anti-inflammatory inhibitory, which is helpful for the development of diabetes and oxidative stress associated disease[1].
• Target Antigen: Amylases
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Cancer; Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/α-amylase-in-3.html
• Solubility: DMSO : 11.11 mg/mL (ultrasonic;warming;heat to 80°C)
• Smiles: O=C(C1=CC2=CC=CC=C2O1)C3=CC=C([N+]([O-])=O)C=C3
• Molecular Weight: 267.24
• References & Citations: [1]Na Li, et al. Design, synthesis and biological evaluation of novel plumbagin derivatives as potent antitumor agents with STAT3 inhibition. Bioorg Chem. 2020 Nov;104:104208.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported