NF-E4 rabbit pAb

NF-E4 rabbit pAb

• Description: The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008],
• Synonyms: Transcription factor NF-E4
• Gene ID: 58160
• UniProt: Q86UQ8
• Cellular Locus: Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Rat, Mouse,
• Immunogen: Synthesized peptide derived from human NF-E4
• Clonality: Polyclonal
• Validated Applications: IHC, IF, WB
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: IHC-p 1:50-200, WB 1:500-2000
• Molecular Weight: 19kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.