NF-E4 rabbit pAb

• Description:

  The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008],

• Synonyms:

  Transcription factor NF-E4

• Gene ID:

  58160

• UniProt:

  Q86UQ8

• Cellular Locus:

  Nucleus.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse,

• Immunogen:

  Synthesized peptide derived from human NF-E4

• Clonality:

  Polyclonal

• Validated Applications:

  IHC, IF, WB

• Stability:

  1 year

• Concentration:

  1 mg/mL

• Dilution:

  IHC-p 1:50-200, WB 1:500-2000

• Molecular Weight:

  19kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.