Palivizumab
CAT:
804-HY-P9944-01
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: Yes
Palivizumab
- CAS Number: 188039-54-5
- UNSPSC Description: Palivizumab (MEDI 493) is a humanized monoclonal antibody against respiratory syncytial virus (RSV). Palivizumab can bind to RSV F protein with a Kd value of 1.4 nM. Palivizumab can prevent respiratory syncytial virus infection in cotton mice[1].
- Target Antigen: RSV
- Type: Inhibitory Antibodies
- Related Pathways: Anti-infection
- Applications: COVID-19-anti-virus
- Field of Research: Infection; Inflammation/Immunology; Cancer
- Assay Protocol: https://www.medchemexpress.com/palivizumab.html
- Purity: 99.43
- Solubility: H2O
- Smiles: [Palivizumab]
- References & Citations: [1]Johnson S, et al. Development of a humanized monoclonal antibody (MEDI-493) with potent in vitro and in vivo activity against respiratory syncytial virus. J Infect Dis. 1997 Nov;176(5):1215-24. |[2]Jacobino SR, et al. Reformatting palivizumab and motavizumab from IgG to human IgA impairs their efficacy against RSV infection in vitro and in vivo. MAbs. 2018 Apr;10(3):453-462. |[3]Piedimonte G, et al. A humanized monoclonal antibody against respiratory syncytial virus (palivizumab) inhibits RSV-induced neurogenic-mediated inflammation in rat airways. Pediatr Res. 2000 Mar;47(3):351-6.
- Shipping Conditions: Dry Ice
- Storage Conditions: Store at -80°C for 2 years
- Clinical Information: Launched