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Palivizumab

CAT: 0804-HY-P9944-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P9944-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Palivizumab (MEDI 493) is a humanized monoclonal antibody against respiratory syncytial virus (RSV) . Palivizumab can bind to RSV F protein with a Kd value of 1.4 nM. Palivizumab can prevent respiratory syncytial virus infection in cotton mice[1].
CAS Number
188039-54-5
Product Name Alternative
MEDI 493
UNSPSC
12352203
Target
RSV
Type
Inhibitory Antibodies
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/palivizumab.html
Purity
99.63
Solubility
H2O
Smiles
[Palivizumab]
Molecular Weight
(145.5 kDa)
References & Citations
[1]Johnson S, et al. Development of a humanized monoclonal antibody (MEDI-493) with potent in vitro and in vivo activity against respiratory syncytial virus. J Infect Dis. 1997 Nov;176 (5) :1215-24. |[2]Jacobino SR, et al. Reformatting palivizumab and motavizumab from IgG to human IgA impairs their efficacy against RSV infection in vitro and in vivo. MAbs. 2018 Apr;10 (3) :453-462. |[3]Piedimonte G, et al. A humanized monoclonal antibody against respiratory syncytial virus (palivizumab) inhibits RSV-induced neurogenic-mediated inflammation in rat airways. Pediatr Res. 2000 Mar;47 (3) :351-6.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched

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