Autotaxin Human Recombinant

• Description:

  Autotaxin Human Recombinant _x000D_ Catalog number: B2016926_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 µg_x000D_ Molecular Weight or Concentration: 96.2 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: ATX, EC 3.1.1.39, Ectonucleotide Pyrophosphatase/Phosphodiesterase-2, ENPP-2, Lyso-PLD, Lysophospholipase D_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Song Y, Dilger E, Bell J, Barton WA, Fang X. Large scale purification and characterization of recombinant human autotaxin/lysophospholipase D from mammalian cells BMB Rep. 2010 Aug;43(8):541-6._x000D_ 2: Nakamura K, Igarashi K, Ide K, Ohkawa R, Okubo S, Yokota H, Masuda A, Oshima N, Takeuchi T, Nangaku M, Okudaira S, Arai H, Ikeda H, Aoki J, Yatomi Y. Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation Clin Chim Acta. 2008 Feb;388(1-2):51-8._x000D_ 3: Gaetano CG, Samadi N, Tomsig JL, Macdonald TL, Lynch KR, Brindley DN. Inhibition of autotaxin production or activity blocks lysophosphatidylcholine-induced migration of human breast cancer and melanoma cells Mol Carcinog. 2009 Sep;48(9):801-9._x000D_ 4: Bolier R, Tolenaars D, Kremer AE, Saris J, Parés A, Verheij J, Bosma PJ, Beuers U, Oude Elferink RPJ. Enteroendocrine cells are a potential source of serum autotaxin in men Biochim Biophys Acta. 2016 Apr;1862(4):696-704._x000D_ 5: Zhao Y, Hasse S, Vaillancourt M, Zhao C, Davis L, Boilard E, Fortin P, Di Battista J, Poubelle PE, Bourgoin SG. Phospholipase A1 Member A Activates Fibroblast-like Synoviocytes through the Autotaxin-Lysophosphatidic Acid Receptor Axis Int J Mol Sci. 2021 Nov 24;22(23):12685._x000D_ 6: Wu JM, Xu Y, Skill NJ, Sheng H, Zhao Z, Yu M, Saxena R, Maluccio MA. Autotaxin expression and its connection with the TNF-alpha-NF-kappaB axis in human hepatocellular carcinoma Mol Cancer. 2010 Mar 31;9:71._x000D_ 7: Haga A, Hashimoto K, Tanaka N, Nakamura KT, Deyashiki Y. Scalable purification and characterization of the extracellular domain of human autotaxin from prokaryotic cells Protein Expr Purif. 2008 May;59(1):9-17._x000D_ 8: Kawagoe H, Stracke ML, Nakamura H, Sano K. Expression and transcriptional regulation of the PD-Ialpha/autotaxin gene in neuroblastoma Cancer Res. 1997 Jun 15;57(12):2516-21._x000D_ 9: Sato K, Malchinkhuu E, Muraki T, Ishikawa K, Hayashi K, Tosaka M, Mochiduki A, Inoue K, Tomura H, Mogi C, Nochi H, Tamoto K, Okajima F. Identification of autotaxin as a neurite retraction-inducing factor of PC12 cells in cerebrospinal fluid and its possible sources J Neurochem. 2005 Feb;92(4):904-14._x000D_ 10: David M, Wannecq E, Descotes F, Jansen S, Deux B, Ribeiro J, Serre CM, Grès S, Bendriss-Vermare N, Bollen M, Saez S, Aoki J, Saulnier-Blache JS, Clézardin P, Peyruchaud O. Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts PLoS One. 2010 Mar 17;5(3):e9741. _x000D_ _x000D_ Products Related to Autotaxin Human Recombinant can be found at Proteins

• Short Description:

  Catalog Number: B2016926 (50 µg)_x000D_ Autotaxin Human Recombinant is a high quality enzyme that plays a key role in the production of lysophosphatidic acid (LPA), a lipid signaling molecule involved in various physiological processes such as cell proliferation, migration, and inflammation. Autotaxin is also known as ENPP2 (ectonucleotide pyrophosphatase/phosphodiesterase 2). This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3