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OU749

CAT: 0804-HY-126710-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126710-02Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
OU749 is a potent γ-glutamyl transpeptidase (GGT) inhibitor with a Ki value of 17.6 µM. OU749 shows cytotoxicity[1].
CAS Number
519170-13-9
UNSPSC
12352005
Hazard Statement
H302
Target
γ-Glutamyl Transferase (GGT)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ou749.html
Concentration
10mM
Purity
98.83
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=CC=C1)(NC2=NN=C(CC3=CC=C(OC)C=C3)S2)=O
Molecular Formula
C16H15N3O3S2
Molecular Weight
361.44
Precautions
H302
References & Citations
[1]King JB, et al. A novel, species-specific class of uncompetitive inhibitors of gamma-glutamyl transpeptidase. J Biol Chem. 2009 Apr 3;284 (14) :9059-65.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

N-(5-(4-methoxybenzyl)-1,3,4-thiadiazol-2-yl)benzenesulfonamide

structure in first source

CAS Number519170-13-9
PubChem CID2177065
IUPAC NameN-[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]benzenesulfonamide
Molecular FormulaC16H15N3O3S2
Molecular Weight361.4
XLogP2.8
Topological Polar Surface Area118
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Heavy Atom Count24
Formal Charge0
Complexity483
SMILES
COC1=CC=C(C=C1)CC2=NN=C(S2)NS(=O)(=O)C3=CC=CC=C3
InChI
InChI=1S/C16H15N3O3S2/c1-22-13-9-7-12(8-10-13)11-15-17-18-16(23-15)19-24(20,21)14-5-3-2-4-6-14/h2-10H,11H2,1H3,(H,18,19)
InChIKey
QCXWBMZVLJCKHF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(5-(4-methoxybenzyl)-1,3,4-thiadiazol-2-yl)benzenesulfonamide
CAS: 519170-13-9
CID: 2177065
Formula: C16H15N3O3S2
MW: 361.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight361.4
XLogP32.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass361.05548370
Monoisotopic Mass361.05548370
Topological Polar Surface Area118 Ų
Heavy Atom Count24
Formal Charge0
Complexity483
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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CatalogName
C4135-25OU749

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