Products for Research Use Only

Proscillaridin A (Standard)

CAT: 0804-HY-N2331RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N2331RSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Proscillaridin A (Standard) is the analytical standard of Proscillaridin A. This product is intended for research and analytical applications. Proscillaridin A is a potent poison of topoisomerase I/II activity with IC50 values of 30 nM and 100 nM, respectively[1].
CAS Number
466-06-8
UNSPSC
12352005
Target
Reference Standards; Topoisomerase
Type
Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/proscillaridin-a-standard.html
Smiles
O[C@@]([C@@]1(CC2)C)(CC[C@@H]1C(C=C3)=COC3=O)[C@@](CCC4=C[C@@H](O[C@@](O[C@@H](C)[C@H](O)[C@H]5O)([H])[C@@H]5O)CC6)([H])[C@@]2([H])[C@]46C
Molecular Formula
C30H42O8
Molecular Weight
530.65
References & Citations
[1]Bielawski K, et al. Inhibition of DNA topoisomerases I and II, and growth inhibition of breast cancer MCF-7 cells by ouabain, digoxin and proscillaridin A.Biol Pharm Bull. 2006 Jul;29 (7) :1493-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards