Digeranyl bisphosphonate
CAT:
804-HY-U00145-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Digeranyl bisphosphonate
- CAS Number: 878143-03-4
- UNSPSC Description: Digeranyl bisphosphonate (DGBP) is a potent geranylgeranylpyrophosphate (GGPP) synthase inhibitor, which inhibits geranylgeranylation of Rac1.
- Target Antigen: Ras
- Type: Reference compound
- Related Pathways: GPCR/G Protein;MAPK/ERK Pathway
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/Phosphonic_acid,_[_3E_-1-[_2E_-3,7-dimethyl-2,6-octadienyl]-4,8-dimethyl-3,7-nonadienylidene]bis-,_tetrasodium_salt.html
- Purity: 98.50
- Solubility: DMSO : 2 mg/mL (ultrasonic)|H2O : 2 mg/mL (ultrasonic)
- Smiles: C/C(C)=C\CC/C(C)=C/CC(P(O[Na])(O[Na])=O)(P(O[Na])(O[Na])=O)C/C=C(C)/CC/C=C(C)\C
- Molecular Weight: 536.40
- References & Citations: [1]Osborn-Heaford HL, et al. Targeting the isoprenoid pathway to abrogate progression of pulmonary fibrosis. Free Radic Biol Med. 2015 Sep;86:47-56.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported