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Cpn10 Antibody (APC)

CAT: 0013-GTR18029372Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18029372Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to Cpn10 (APC) . Chaperonin 10, otherwise known as Cpn10, (groES in E. coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (Hsp10s) . Cpn10 acts as a co-chaperone and interacts with the Hsp60 family to promote proper folding of polypeptides. Cpn10 and Cpn60 both exhibit sevenfold axis of symmetry and function as a team in the protein folding and assembly process. Cpn10 has been located in human platelets, but is also present in human maternal serum. It has been reported that human Cpn10 is identical with early pregnancy factor, which is involved in control over cell growth and development. This identification suggest that Cpn10 may act like a hormone in stressful situations such as pregnancy..
Product Name Alternative
10kDa Chaperonin, Chaperonin 10, Cpn 10, EPF, GROES, Heat Shock 10kD protein1, HSP10, HSPE1
UniProt
P61604
Reactivity
Bovine, Canine, Frog, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep
Immunogen
Human Cpn10 peptide AA 91-101
Target
Cpn10
Clonality
Polyclonal
Conjugation
APC
Field of Research
Cancer Biology, Cell Biology, Metabolism Research, Protein Biochemistry, Signal Transduction
Purification
Protein A Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), IHC (1:100)
Molecular Weight
10kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of Cpn10 in 10 μg of Hela lysates by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
Tested Applications
ELISA, ICC, IF, IHC, IP, WB
NCBI Accession Number
NP_002148.1
Host or Source
Rabbit
Preservative
95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Entrez
3336

UniProtKB · P61604

10 kDa heat shock protein, mitochondrial

CH10_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P61604
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HSPE1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Hsp10
EC number
—
Processing
—
Secondary accessions
O95421, Q04984, Q53X54, Q9UDH0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Molecular function

Chaperone

Cellular component

Mitochondrion

Biological process

Stress response

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