Products for Research Use Only
RegisterLogin

Mitofusin 2 Antibody (APC)

CAT: 0013-GTR18029078Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18029078Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Mouse monoclonal to Mitofusin 2 (APC) . Mitofusin-2 (Mfn2) is a membrane protein of the mitochondria and is important in mitochondrial fusion in mammalian cells. Mfn2 activity has also been implicated in mitochondrial metabolism and the loss of Mfn2 may be the reason for certain metabolic modifications that are seen in individuals with obesity. Mfn2 has been associated with maintaining the membrane potential of the mitochondria. Mfn2 has been shown to hinder mitochondrial antiviral signaling by inhibiting production of type 1 interferons. Mfn2 is a p53-inducible target and involved in cell proliferation, apoptosis promotion and tumor suppression..
Product Name Alternative
Mitofusin 2, MFN2, Mfn2, Mitofusin-2, Transmembrane GTPase MFN2, Mitochondrial assembly regulatory factor, MARF, CMT2A, CMT2A2, CPRP1, CPRP 1, Fzo, HSG, Hyperplasia suppressor gene, Hypertension related protein 1, KIAA0214
UniProt
Q80U63
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein amino acids 370-600 (cytoplasmic N-terminus) of mouse Mitofusin-2. Rat: 97% identity (226/231 amino acids identical) . Human: 92% identity (214/231 amino acids identical) ~55% identity with Mitofusin-1.
Target
Mitofusin 2
Clonality
Monoclonal
Clone
N153/5 (Formerly sold as S153-5)
Conjugation
APC
Field of Research
Cancer Biology, Cell Biology, Disease Biomarkers, Neuroscience, Signal Transduction
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), ICC/IF (1:100)
Molecular Weight
90kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of Mitofusin-2 in 20 μg of mouse cardiac mitochondrial lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Tested Applications
ICC, IF, IHC, WB
NCBI Accession Number
NP_573464.2
Host or Source
Mouse
Preservative
95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Isotype
IgG2a
Entrez
170731

UniProtKB · Q80U63

Mitofusin-2

MFN2_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q80U63
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Mfn2
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
3.6.5.-
Processing
—
Secondary accessions
A2A7Y7, A8Y5E4, Q3V3B8, Q80WP4, Q80XK3, Q8BHF0, Q8BKV5, Q8R535, Q923X2
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisAutophagyUnfolded protein response

Domain

Coiled coilTransmembraneTransmembrane helix

Molecular function

Developmental proteinHydrolase

Technical term

Direct protein sequencingReference proteome

Ligand

GTP-bindingNucleotide-binding

Cellular component

MembraneMitochondrionMitochondrion outer membrane

PTM

PhosphoproteinUbl conjugation

Related Products

CatalogName
GTR17816677Mitofusin 2 Rabbit Polyclonal Antibody (APC)
GTR18455546Mitofusin 2 Rabbit Polyclonal Antibody (APC-Cy7)
GTR18567308Mitofusin 2/MFN2 Rabbit Polyclonal Antibody (APC)
GTR18074812-01Mitofusin 2 Antibody
GTR18080407Mitofusin 2 Antibody
GTR19019608-01Mitofusin-2
GTR19013668-01Mitofusin-2
GTR19015235-01Mitofusin-2
GTR18455657Mitofusin 2 Rabbit Polyclonal Antibody (APC-Cy5.5)
GTR18300711-01Mitofusin 2 polyclonal antibody

Alternative Products

CatalogName
abx446782Mitofusin 2 (MFN2) Antibody (APC)
bsm-61395R-APC-01Mitofusin 2 Recombinant Antibody, APC Conjugated
bs-0557R-APCMitofusin 1 Polyclonal Antibody, APC Conjugated
bsm-61383R-APC-TRMitofusin 1 Recombinant Antibody, APC Conjugated
MBS2067177-01APC-Linked Polyclonal Antibody to Mitofusin 1 (MFN1)
MBS2165639-01APC-Linked Polyclonal Antibody to Mitofusin 2 (MFN2)
bsm-61395R-APC-Cy7Mitofusin 2 Recombinant Antibody, APC-Cy7 Conjugated
bsm-61383R-APC-Cy7Mitofusin 1 Recombinant Antibody, APC-Cy7 Conjugated
bs-0557R-APC-Cy7Mitofusin 1 Polyclonal Antibody, APC-Cy7 Conjugated
bsm-61383R-APC-Cy5.5Mitofusin 1 Recombinant Antibody, APC-Cy5.5 Conjugated

Popular Products