Products for Research Use Only

VDAC1 Antibody (FITC)

CAT: 0013-GTR18029074Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18029074Size:100 µg
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Description
Mouse monoclonal to VDAC1 (FITC) . Voltage-dependent anion-selective channel protein 1 (also known as VDAC, VDAC1 or outer mitochondrial membrane protein porin 1) is the the outer mitochondrial membrane receptor for hexokinase and BCL2L1. VDAC forms a channel through the mitochondrial membrane and is involved in small molecule diffusion, cell volume regulation and apoptosis. VDAC may participate in the formation of the permeability transition pore complex (PTPC), which is responsible for the release of mitochondrial products that triggers apoptosis..
Product Name Alternative
Voltage Dependent Anion Channel 1, Porin, Voltage dependent anion selective channel protein 1, Voltage-dependent anion-selective channel protein 1, hVDAC1, MGC111064, Mitochondrial Porin, Outer mitochondrial membrane protein porin 1, Plasmalemmal porin, Porin 31HL, Porin 31HM, PORIN-31-HL, VDAC 1, VDAC, VDAC-1
UniProt
P21796
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein amino acids 1-283 (full-length) of human VDAC1. Mouse: 98% identity (279/283 amino acids identical) . Rat: 98% identity (279/283 amino acids identical) > 60% identity with VDAC2 and VDAC3.
Target
VDAC1
Clonality
Monoclonal
Clone
N152B/23 (Formerly sold as S152B-23)
Conjugation
FITC
Field of Research
Cell Biology
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000)
Molecular Weight
30kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of VDAC1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Tested Applications
ICC, IF, IHC, WB
NCBI Accession Number
NP_003365.1
Host or Source
Mouse
Preservative
640.91mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09mM phosphates, 9.09mM NaHCO3
Isotype
IgG2a
Entrez
7416

UniProtKB · P21796

Non-selective voltage-gated ion channel VDAC1

VDAC1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P21796
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
VDAC1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B3KVK4, D3DQ93, Q5FVE7, Q9UIQ5, Q9UPL0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Biological process

ApoptosisHost-virus interactionIon transportLipid transportTransport

Ligand

ATP-bindingLipid-bindingNADNucleotide-binding

Cellular component

Cell membraneMembraneMitochondrionMitochondrion outer membrane

Molecular function

Porin

Domain

TransmembraneTransmembrane beta strand