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TRPC7 Antibody (FITC)

CAT: 0013-GTR18028761Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18028761Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse monoclonal to TrpC7 (FITC) . Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a non-selective cation channel that is directly activated by DAG. TrpC7 shows constitutive activity and susceptibility to negative regulation by extracellular Ca2+. Because of this, TrpC7 plays an important role in the Ca2+ signaling pathway. TrpC7 is also expressed abundantly in the heart, and combined with its ability to act as a Ca2+ channel, TrpC7 might contribute to the process of heart failure..
Product Name Alternative
TRP7, KNP3, TRPM2, transient receptor potential cation channel subfamily C member 7
UniProt
Q9HCX4
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide amino acids 845-862 of human TRPC7
Target
TRPC7
Clonality
Monoclonal
Clone
N64A/36 (Formerly sold as S64A-36)
Conjugation
FITC
Field of Research
Neuroscience
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), IHC (1:1000), ICC/IF (1:100)
Molecular Weight
100kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of TrpC7 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Tested Applications
AM, ICC, IF, IHC, IP, WB
NCBI Accession Number
NP_065122.1
Host or Source
Mouse
Preservative
640.91mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09mM phosphates, 9.09mM NaHCO3
Isotype
IgG1
Entrez
57113

UniProtKB · Q9HCX4

Short transient receptor potential channel 7

TRPC7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9HCX4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TRPC7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
TrpC7
EC number
—
Processing
—
Secondary accessions
A1A4Z4, F5H5U9, Q70T26, Q8IWP7
Protein keywords

Coding sequence diversity

Alternative splicing

Domain

ANK repeatRepeatTransmembraneTransmembrane helix

Ligand

Calcium

Molecular function

Calcium channelIon channel

Biological process

Calcium transportIon transportTransport

Cellular component

Cell membraneMembraneNucleus

PTM

GlycoproteinPhosphoprotein

Technical term

Reference proteome

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