Products for Research Use Only
RegisterLogin

Vorapaxar-d5

CAT: 0804-HY-10119SSize: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-10119SSize:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Vorapaxar-d5 is deuterated labeled Vorapaxar. Vorapaxar (SCH 530348), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM). Vorapaxar (SCH 530348) inhibits thrombin receptor-activating peptide (TRAP) -induced platelet aggregation in a dose-dependent manner[1].
Product Name Alternative
SCH 530348-d5
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Protease Activated Receptor (PAR)
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Solubility
10 mM in DMSO
Smiles
FC1=C(C=CC=C1)C(C=N2)=CC=C2/C=C/[C@@H](C(C(C3)C4)CC[C@H]3NC(OC([2H])(C([2H])([2H])[2H])[2H])=O)C5C4C(O[C@@H]5C)=O
Molecular Formula
C29H28D5FN2O4
Molecular Weight
497.61
References & Citations
[1]Khoufache K, et al. PAR1 contributes to influenza A virus pathogenicity in mice. J Clin Invest. 2013 Jan;123 (1) :206-14.|[2]Kehinde O, et al. Vorapaxar: A novel agent to be considered in the secondary prevention of myocardial infarction. J Pharm Bioallied Sci. 2016 Apr-Jun;8 (2) :98-105.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-10119-01Vorapaxar
HY-10119R-01Vorapaxar (Standard)
HY-10119A-01Vorapaxar (sulfate)
HY-10119ARVorapaxar (sulfate) (Standard)
HY-151913S-01Sebuthylazine-d5 (ethyl-d5)
HY-W717221Medetomidine-d5 (d5-Major)
HY-133171AS-01(S) -Norfluoxetine-d5 (phenyl-d5)
HY-151910S1(±) -Fluoxetine-d5 Oxalate (phenyl-d5)
HY-W758414Phoxim-d5 (phenyl-d5) (mixture of isomers)
HY-133171AS1-01(R) -Norfluoxetine-d5 Phthalimide (Phenyl-d5)

Alternative Products

CatalogName
CS-O-15171Vorapaxar-d5
TRC-V758202-25MGVorapaxar-d5 Sulfate
A8809-100Vorapaxar
TRC-V758200-50MGVorapaxar Sulfate

Popular Products