Products for Research Use Only
RegisterLogin

Vorapaxar

CAT: 0804-HY-10119-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-10119-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Vorapaxar (SCH 530348), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM) . Vorapaxar (SCH 530348) inhibits thrombin receptor-activating peptide (TRAP) -induced platelet aggregation in a dose-dependent manner[1].
CAS Number
618385-01-6
Product Name Alternative
SCH 530348
UNSPSC
12352005
Hazard Statement
H371, H373, H400, H410
Target
Protease Activated Receptor (PAR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Vorapaxar.html
Purity
99.85
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(O[C@@H]1C)[C@@]2([H])[C@]1([H])[C@@H](/C=C/C3=NC=C(C=C3)C4=CC=CC(F)=C4)[C@]([C@](C5)([H])C2)([H])CC[C@H]5NC(OCC)=O
Molecular Formula
C29H33FN2O4
Molecular Weight
492.58
Precautions
H371, H373, H400, H410
References & Citations
[1]Khoufache K, et al. PAR1 contributes to influenza A virus pathogenicity in mice. J Clin Invest. 2013 Jan;123 (1) :206-14.|[2]Kehinde O, et al. Vorapaxar: A novel agent to be considered in the secondary prevention of myocardial infarction. J Pharm Bioallied Sci. 2016 Apr-Jun;8 (2) :98-105.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
PAR1

Alternative Products

CatalogName
A8809-100Vorapaxar
CS-O-15171Vorapaxar-d5
TRC-V758200-50MGVorapaxar Sulfate

Popular Products