Poliovirus Receptor Recombinant Rabbit Monoclonal Antibody [JE45-53]

• Description:

  CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication.

• Product Name Alternative:

  CD155 antibody CD155 antigen antibody FLJ25946 antibody HVED antibody mE4 antibody NECL 5 antibody Necl-5 antibody Necl5 antibody Nectin like 5 antibody Nectin like protein 5 antibody Nectin-like protein 5 antibody Ortholog of mouse Tage4 antibody Poliovirus receptor antibody PVR antibody PVR_HUMAN antibody PVS antibody Taa1 antibody Tage 4 antibody TAGE4 antibody

• Abbreviation:

  PVR, PV5

• Swiss Prot:

  P15151 Human

• Cellular Locus:

  Cell membrane, Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human

• Immunogen:

  Synthetic peptide.

• Isotype:

  IgG

• Clone:

  JE45-53

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IF-Cell

• Positive Control:

  HUVEC cell lysate, U87-MG cell lysate, A549 cell lysates, HUVEC.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000-1:2,000 ;IF-Cell: 1:100

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 45 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3