Mirogabalin besylate
CAT:
804-HY-108006-02
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Mirogabalin besylate
- CAS Number: 1138245-21-2
- UNSPSC Description: Mirogabalin besylate is a selective and orally available ligand for the α2δ subunit of voltage-gated calcium channels, with Kds of 13.5 nM, 22.7 nM, 27 nM, and 47.6 nM for human α2δ-1, human α2δ-2, rat α2δ-1, and rat α2δ-2, respectively.
- Target Antigen: Calcium Channel
- Type: Reference compound
- Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/Mirogabalin_besylate.html
- Purity: 99.57
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=S(C1=CC=CC=C1)(O)=O.OC(C[C@@]2([C@@]3([H])[C@@](CC(CC)=C3)([H])C2)CN)=O
- Molecular Weight: 367.46
- References & Citations: [1]Domon Y, et al. Binding Characteristics and Analgesic Effects of Mirogabalin, a Novel Ligand for the α2δ Subunit of Voltage-Gated Calcium Channels. J Pharmacol Exp Ther. 2018 Jun;365(3):573-582.Cell Commun Signal. 2024 Feb 1;22(1):92.|Brain Behav Immun. 2021 Jul;95:344-361.|Molecules. 2023 Nov 30, 28(23), 7862.|Pharmaceuticals. 2022, 15(1), 88.|Pharmaceuticals. 2023 Jul 19, 16(7), 1023.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: Phase 3