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S-309309

CAT: 0804-HY-159422-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-159422-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
S-309309 is an orally active and selective MGAT2 inhibitor. S-309309 can be used in metabolism-related research[1].
CAS Number
2267352-04-3
UNSPSC
12352005
Target
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/s-309309.html
Purity
98.55
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC1=CC(F)=CC2=C1[C@]3(NC(C4=C(NC(CS(C)(=O)=O)=O)N(C5=CC=C(C)C=N5)N=C4C3)=O)CCO2
Molecular Formula
C23H21F2N5O5S
Molecular Weight
517.51
References & Citations
[1]Miyano T, et al. The Continuous and Reversible Transformation of the Polymorphs of an MGAT2 Inhibitor (S-309309) from the Anhydrate to the Hydrate in Response to Relative Humidity. Pharmaceutics. 2024 Jul 17;16 (7) :949.|[2]YOSHIKI RYO, et al. 1649-P: S-309309, a Novel MGAT2 Inhibitor, Enhances Intestinal Fatty Acid Beta Oxidation and Provides Metabolic Benefits in DIO Mice. Diabetes, 2024, 73 (Supplement_1) .
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
MGAT2

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