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Lamivudine

CAT: 0804-HY-B0250-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0250-01Size:100 mg
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Description
Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI) . Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS[1][2].
CAS Number
134678-17-4
Product Name Alternative
BCH-189
UNSPSC
12352005
Hazard Statement
H361
Target
HBV; HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/Lamivudine.html
Concentration
10mM
Purity
99.99
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL
Smiles
OC[C@H]1SC[C@@H](N2C(N=C(N)C=C2)=O)O1
Molecular Formula
C8H11N3O3S
Molecular Weight
229.26
Precautions
H361
References & Citations
[1]Colledge D, et al. Synergistic inhibition of hepadnaviral replication by lamivudine in combination with penciclovir in vitro. Hepatology. 1997 Jul;26 (1) :216-25. |[2]Olaniyan LW, et al. Lamivudine-Induced Liver Injury. Open Access Maced J Med Sci. 2015 Dec 15;3 (4) :545-50. |[3]Mdanda S, et al. Zidovudine and Lamivudine as Potential Agents to Combat HIV-Associated Neurocognitive Disorder. Assay Drug Dev Technol. 2019 Oct;17 (7) :322-329.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

Alternative Products

CatalogName
NL06295-01Lamivudine

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